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| 生物转化在生态毒理学中的作用 Role of Biotransformation in Ecotoxicology | |||
| 分会内容： | Pollutants undergo biotransformation in the environment and within organisms. Reactions include hydrolysis, oxidation-reduction, polymerization, or conjugation. The physicochemical properties of the transformation products may significantly differ from those of the parent compounds. As a consequence, biotransformation may distinctly change the environmental behavior, fate, toxicokinetics and toxicodynamics of the parent pollutants. Thus, a comprehensive understanding of the fate and effects of both parent compounds and transformation products is crucial for assessing the ecological risks of pollutants. To address this critical scientific question, the topics of this session mainly focus on the biotransformation of various pollutants within environmental media and biological organisms, including: (1) identification of biotransformation products using multiple target and non-target analysis strategies, (2) unveiling the biotransformation pathways, impact factors, and structure-effect relationships, and (3) assessment of the bioavailability and toxicological effects of both parent compounds and their transformation products, aiming to elucidate the underlying mechanisms behind these toxic effects. | ||
| 召集人： | Schlenk, Daniel 祝凌燕 | 美国 中国 | 美国加州大学河滨分校 南开大学 |
| 联系人/秘书： | 仪淑君，南开大学，shujun_yi@nankai.edu.cn | ||
